ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein–protein interactions with HPRT1

Gout, a common form of inflammatory arthritis, is strongly associated with elevated uric acid concentrations in the blood (hyperuricemia). A recent study in Icelanders identified a rare missense single nucleotide polymorphism (SNP) in the ALDH16A1 gene, ALDH16A1*2, to be associated with gout and ser...

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Main Authors: Vasiliou, Vasilis, Sandoval, Monica, Backos, Donald S., Jackson, Brian C., Chen, Ying, Reigan, Philip, Lanaspa, Miguel A., Johnson, Richard J., Koppaka, Vindhya, Thompson, David C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746320/
https://ncbi.nlm.nih.gov/pubmed/23348497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.12.018
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