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Clearance of lysosomal glycogen accumulation by Transcription factor EB (TFEB) in muscle cells from lysosomal alpha-glucosidase deficient mice

A recently proposed therapeutic approach for lysosomal storage disorders (LSDs) relies upon the ability of transcription factor EB (TFEB) to stimulate autophagy and induce lysosomal exocytosis leading to cellular clearance. This approach is particularly attractive in Glycogen Storage Disease type II...

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Bibliografski detalji
Glavni autori: Li, Hoi Ming, Feeney, Erin, Li, Lishu, Zare, Hossein, Puertollano, Rosa, Raben, Nina
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687018/
https://ncbi.nlm.nih.gov/pubmed/23416076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.02.026
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