EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia vs. benign lesions

PURPOSE: Promoter hypermethylation has been recently proposed as a mean for HNSCC detection in salivary rinses. In a prospective study of a high-risk population, we showed that EDNRB promoter methylation in salivary rinses is a useful biomarker for oral cancer and premalignancy. EXPERIMENTAL DESIGN:...

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Autors principals: Schussel, Juliana, Zhou, Xian Chong, Zhang, Zhe, Pattani, Kavita, Bermudez, Francisco, Jean-Charles, Germain, McCaffrey, Thomas, Padhya, Tapan, Phelan, Joan, Spivakovsky, Silvia, Brait, Mariana, Li, Ryan, Bowne, Helen Yoo, Goldberg, Judith D., Rolnitzky, Linda, Robbins, Miriam, Kerr, A. Ross, Sirois, David, Califano, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687013/
https://ncbi.nlm.nih.gov/pubmed/23637120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3496
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