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Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer

OBJECTIVE: Colorectal cancer (CRC) is one of the most common digestive malignancies in the world. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. However, the function of EDNRB gene in CRC remains un...

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Autori principali: Chen, Cheng, Wang, Lingyan, Liao, Qi, Huang, Yi, Ye, Huadan, Chen, Fei, Xu, Leiting, Ye, Meng, Duan, Shiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029727/
https://ncbi.nlm.nih.gov/pubmed/24326135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-8-199
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