Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance

PURPOSE: Hypermethylation of tumor suppressor gene promoters has been found in head and neck squamous carcinoma (HNSCC) and other solid tumors. We evaluated these alterations in pretreatment salivary rinses from HNSCC patients by using real-time quantitative methylation-specific PCR (Q-MSP). EXPERIM...

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Autors principals: Carvalho, André Lopes, Henrique, Rui, Jeronimo, Carmen, Nayak, Chetan S., Reddy, Ashok N., Hoque, Mohammad O., Chang, Steven, Brait, Mariana, Jiang, Wei-Wen, Kim, Michael M., Claybourne, Quia, Goldenberg, David, Khan, Zubair, Khan, Tanbir, Westra, William H., Sidransky, David, Koch, Wayne, Califano, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215270/
https://ncbi.nlm.nih.gov/pubmed/21628494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0324
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