MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast Cancer

Overexpression of the pro-metastatic chromatin modifier protein MTA1 in human cancer contributes to tumor aggressiveness, but the role of endogenous MTA1 in cancer has not been explored. Here we report the effects of selective genetic depletion of MTA1 in a physiologically relevant spontaneous mouse...

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Autors principals: Pakala, Suresh B., Rayala, Suresh K., Wang, Rui-An, Ohshiro, Kazufumi, Mudvari, Prakriti, Reddy, Sirigiri Divijendra Natha, Zheng, Yi, Pires, Ricardo, Casimiro, Sandra, Pillai, M. Radhakrishna, Costa, Luis, Kumar, Rakesh
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686857/
https://ncbi.nlm.nih.gov/pubmed/23580571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3998
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