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E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
Metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling and histone deacetylation (NuRD) complex, is widely upregulated in human cancers. However, the mechanism for regulating its protein stability remains unknown. Here we report that MTA1 is an ubiquitinated protein and tar...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762678/ https://ncbi.nlm.nih.gov/pubmed/19805145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908027106 |
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