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MTA1 Coregulator Regulates p53 Stability and Function

Although metastasis-associated protein 1 (MTA1) has recently been shown as a DNA damage responsive protein, the underlying mechanism for its role in DNA double-strand break (DSB) repair remains unknown. Here, we show that MTA1 controls p53 stability through inhibiting its ubiquitination by E3 ubiqui...

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Detalhes bibliográficos
Main Authors: Li, Da-Qiang, Divijendra Natha Reddy, Sirigiri, Pakala, Suresh B., Wu, Xifeng, Zhang, Yanping, Rayala, Suresh K., Kumar, Rakesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787316/
https://ncbi.nlm.nih.gov/pubmed/19837670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056499
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