MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast Cancer

Overexpression of the pro-metastatic chromatin modifier protein MTA1 in human cancer contributes to tumor aggressiveness, but the role of endogenous MTA1 in cancer has not been explored. Here we report the effects of selective genetic depletion of MTA1 in a physiologically relevant spontaneous mouse...

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Autori principali: Pakala, Suresh B., Rayala, Suresh K., Wang, Rui-An, Ohshiro, Kazufumi, Mudvari, Prakriti, Reddy, Sirigiri Divijendra Natha, Zheng, Yi, Pires, Ricardo, Casimiro, Sandra, Pillai, M. Radhakrishna, Costa, Luis, Kumar, Rakesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686857/
https://ncbi.nlm.nih.gov/pubmed/23580571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3998
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