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The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans

Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles of the secretory pathway. Guanine nucleotide exchange factor (GEFs) activate the small GTPases and help their anchorage in the membrane. Thus, GEFs in a way temporally and...

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Библиографические подробности
Главные авторы: Ackema, Karin B., Sauder, Ursula, Solinger, Jachen A., Spang, Anne
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686754/
https://ncbi.nlm.nih.gov/pubmed/23840591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067076
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