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Fluctuations in Tat copy number when it counts the most: a possible mechanism to battle the HIV latency

The HIV-1 virus can enter a dormant state and become inactive, which reduces accessibility by antiviral drugs. We approach this latency problem from an unconventional point of view, with the focus on understanding how intrinsic chemical noise (copy number fluctuations of the Tat protein) can be used...

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Autori principali: Konkoli, Zoran, Jesorka, Aldo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686706/
https://ncbi.nlm.nih.gov/pubmed/23497153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-10-16
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