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Fluctuations in Tat copy number when it counts the most: a possible mechanism to battle the HIV latency

The HIV-1 virus can enter a dormant state and become inactive, which reduces accessibility by antiviral drugs. We approach this latency problem from an unconventional point of view, with the focus on understanding how intrinsic chemical noise (copy number fluctuations of the Tat protein) can be used...

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Main Authors: Konkoli, Zoran, Jesorka, Aldo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686706/
https://ncbi.nlm.nih.gov/pubmed/23497153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-10-16
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