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Advantage of Using Allele-Specific Copy Numbers When Testing for Association in Regions with Common Copy Number Variants

Copy number variants (CNV) can be called from SNP-arrays; however, few studies have attempted to combine both CNV and SNP calls to test for association with complex diseases. Even when SNPs are located within CNVs, two separate association analyses are necessary, to compare the distribution of bi-al...

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Autors principals: Marenne, Gaëlle, Chanock, Stephen J., Malats, Núria, Génin, Emmanuelle
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769257/
https://ncbi.nlm.nih.gov/pubmed/24040408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075350
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