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Deletion and amplification of the HGPRT locus in Chinese hamster cells.

Somatic cell selective techniques and hybridization analyses with a cloned cDNA probe were used to isolate and identify Chinese hamster cell lines in which the X-linked gene for hypoxanthine-guanine phosphoribosyltransferase (HGPRT) has been altered. Two of 19 HGPRT-deficient mutants selected were f...

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Detalhes bibliográficos
Main Authors: Fuscoe, J C, Fenwick, R G, Ledbetter, D H, Caskey, C T
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368638/
https://ncbi.nlm.nih.gov/pubmed/6877239
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