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Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification.

The application of recombinant DNA technology to prenatal diagnosis of many recessively inherited X-linked diseases is complicated by a high frequency of heterogeneous, new mutations (1). Partial gene deletions account for more than 50% of Duchenne muscular dystrophy (DMD) lesions, and approximately...

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Detalhes bibliográficos
Main Authors: Chamberlain, J S, Gibbs, R A, Ranier, J E, Nguyen, P N, Caskey, C T
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC339001/
https://ncbi.nlm.nih.gov/pubmed/3205741
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