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In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences

The M40 VSV recombinant was engineered to contain overlapping PTAP and PPxY L-domain motifs and flanking residues from the VP40 protein of Ebola virus. Replication of M40 in cell culture is virtually indistinguishable from that of control viruses. However, the presence of the Ebola PTAP motif in the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Irie, Takashi, Carnero, Elena, García-Sastre, Adolfo, Harty, Ronald N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686127/
https://ncbi.nlm.nih.gov/pubmed/23794798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IDRT.S10652
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