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In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences

The M40 VSV recombinant was engineered to contain overlapping PTAP and PPxY L-domain motifs and flanking residues from the VP40 protein of Ebola virus. Replication of M40 in cell culture is virtually indistinguishable from that of control viruses. However, the presence of the Ebola PTAP motif in the...

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Dettagli Bibliografici
Autori principali: Irie, Takashi, Carnero, Elena, García-Sastre, Adolfo, Harty, Ronald N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686127/
https://ncbi.nlm.nih.gov/pubmed/23794798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IDRT.S10652
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