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Functional characterization of Ebola virus L-domains using VSV recombinants
VSV recombinants containing the overlapping L-domain sequences from Ebola virus VP40 (PTAPPEY) were recovered by reverse-genetics. Replication kinetics of M40-WT, M40-P24L, and M40-Y30A were indistinguishable from VSV-WT in BHK-21 cells, whereas the double mutant (M40-P2728A) was defective in buddin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929245/ https://ncbi.nlm.nih.gov/pubmed/15892969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.03.027 |
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