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L-Domain Flanking Sequences Are Important for Host Interactions and Efficient Budding of Vesicular Stomatitis Virus Recombinants

Vesicular stomatitis virus (VSV) possesses a PPPY and a PSAP motif within the matrix (M) protein. The PPPY motif has significant L-domain activity in BHK-21 cells, whereas the PSAP motif does not. Since the core PSAP motif alone is insufficient to provide L-domain activity, we modified upstream or d...

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Autori principali: Irie, Takashi, Harty, Ronald N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235845/
https://ncbi.nlm.nih.gov/pubmed/16188963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12617-12622.2005
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