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Cystic Fibrosis Transmembrane Regulator Correctors and Potentiators

Cystic fibrosis (CF) is caused by loss-of-function mutations in the CF transmembrane conductance regulator (CFTR) protein, a cAMP-regulated anion channel expressed primarily at the apical plasma membrane of secretory epithelia. Nearly 2000 mutations in the CFTR gene have been identified that cause d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rowe, Steven M., Verkman, Alan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685879/
https://ncbi.nlm.nih.gov/pubmed/23818513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009761
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