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Cystic Fibrosis Transmembrane Regulator Correctors and Potentiators
Cystic fibrosis (CF) is caused by loss-of-function mutations in the CF transmembrane conductance regulator (CFTR) protein, a cAMP-regulated anion channel expressed primarily at the apical plasma membrane of secretory epithelia. Nearly 2000 mutations in the CFTR gene have been identified that cause d...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685879/ https://ncbi.nlm.nih.gov/pubmed/23818513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009761 |
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