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Acetylation is indispensable for p53 antiviral activity
Tumor suppressor p53 is known to be a direct transcriptional target of type I interferons (IFNs), contributing to virus-induced apoptosis, and in turn activating itself the interferon pathway. Acetylation, among many other post-translational modifications of p53, is thought to exert a crucial role r...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685621/ https://ncbi.nlm.nih.gov/pubmed/22033337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.21.17899 |
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