α4β2 nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats

L-dopa-induced dyskinesias are a serious long-term side effect of dopamine replacement therapy for Parkinson’s disease for which there are few treatment options. Our previous studies showed that nicotine decreased L-dopa-induced abnormal involuntary movements (AIMs). Subsequent work with knockout mi...

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Bibliographische Detailangaben
Hauptverfasser: Quik, Maryka, Campos, Carla, Bordia, Tanuja, Strachan, Jon-Paul, Zhang, Jenny, McIntosh, J. Michael, Letchworth, Sharon, Jordan, Kristen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685407/
https://ncbi.nlm.nih.gov/pubmed/23583932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.03.038
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