Perinatal Exposure of Patas Monkeys to Antiretroviral Nucleoside Reverse-Transcriptase Inhibitors Induces Genotoxicity Persistent for up to 3 Years of Age

Background. Erythrocebus patas (patas) monkeys were used to model antiretroviral (ARV) drug in human immunodeficiency virus type 1–infected pregnant women. Methods. Pregnant patas dams were given human-equivalent doses of ARVs daily during 50% of gestation. Mesenchymal cells, cultured from bone marr...

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Detalhes bibliográficos
Main Authors: Olivero, Ofelia A., Torres, Lorangelly Rivera, Gorjifard, Sayeh, Momot, Dariya, Marrogi, Eryney, Divi, Rao L., Liu, Yongmin, Woodward, Ruth A., Sowers, Marsha J., Poirier, Miriam C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685224/
https://ncbi.nlm.nih.gov/pubmed/23559463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit146
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