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Human inter-individual variability in metabolism and genotoxic response to zidovudine
A mainstay of the antiretroviral drugs used for therapy of HIV-1, Zidovudine (AZT) is genotoxic and becomes incorporated into DNA. Here we explored host interindividual variability in AZT-DNA incorporation, by AZT radiomimmunoassay (RIA), using 19 different strains of normal human mammary epithelial...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2384225/ https://ncbi.nlm.nih.gov/pubmed/18206198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.12.005 |
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