Human inter-individual variability in metabolism and genotoxic response to zidovudine

A mainstay of the antiretroviral drugs used for therapy of HIV-1, Zidovudine (AZT) is genotoxic and becomes incorporated into DNA. Here we explored host interindividual variability in AZT-DNA incorporation, by AZT radiomimmunoassay (RIA), using 19 different strains of normal human mammary epithelial...

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Bibliografski detalji
Glavni autori: Olivero, Ofelia A., Ming, Jessica M., Das, Shreyasi, Vazquez, Irma L., Richardson, Diana L., Weston, Ainsley, Poirier, Miriam C.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384225/
https://ncbi.nlm.nih.gov/pubmed/18206198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.12.005
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