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Protection of Irf5-deficient mice from pristane-induced lupus involves altered cytokine production and class switching
Polymorphisms in the transcription factor interferon (IFN) regulatory factor 5 (IRF5) have been identified that show strong association with increased risk of developing the autoimmune disease systemic lupus erythematosus (SLE). A potential pathologic role for IRF5 in SLE development is supported by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684952/ https://ncbi.nlm.nih.gov/pubmed/22678902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141642 |
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