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Protection of Irf5-deficient mice from pristane-induced lupus involves altered cytokine production and class switching

Polymorphisms in the transcription factor interferon (IFN) regulatory factor 5 (IRF5) have been identified that show strong association with increased risk of developing the autoimmune disease systemic lupus erythematosus (SLE). A potential pathologic role for IRF5 in SLE development is supported by...

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Bibliografiset tiedot
Päätekijät: Feng, Di, Yang, Lisong, Bi, Xiaohui, Stone, Rivka C., Patel, Priya, Barnes, Betsy J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684952/
https://ncbi.nlm.nih.gov/pubmed/22678902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141642
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