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Differential Requirement of Histone Acetylase and Deacetylase Activities for IRF5-Mediated Proinflammatory Cytokine Expression

Recent evidence indicates a new role for histone deacetylases (HDACs) in the activation of genes governing the host immune response. Virus, along with other pathogenic stimuli, triggers an antiviral defense mechanism through the induction of IFN, IFN-stimulated genes, and other proinflammatory cytok...

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Hlavní autoři: Feng, Di, Sangster-Guity, Niquiche, Stone, Rivka, Korczeniewska, Justyna, Mancl, Margo E., Fitzgerald-Bocarsly, Patricia, Barnes, Betsy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233222/
https://ncbi.nlm.nih.gov/pubmed/20935208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000482
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