The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4

Proliferating mammalian cells use glutamine as a source of nitrogen and as a key anaplerotic source to provide metabolites to the tricarboxylic acid cycle (TCA) for biosynthesis. Recently, mTORC1 activation has been correlated with increased nutrient uptake and metabolism, but no molecular connectio...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Csibi, Alfred, Fendt, Sarah-Maria, Li, Chenggang, Poulogiannis, George, Choo, Andrew Y., Chapski, Douglas J., Jeong, Seung Min, Dempsey, Jamie, Parkhitko, Andrey, Morrison, Tasha, Henske, Elizabeth, Haigis, Marcia, Cantley, Lewis C., Stephanopoulos, Gregory, Yu, Jane, Blenis, John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684628/
https://ncbi.nlm.nih.gov/pubmed/23663782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.023
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller