CD8(+) T Cell Cross-Reactivity Profiles and HIV-1 Immune Escape towards an HLA-B35-Restricted Immunodominant Nef Epitope

Antigen cross-reactivity is an inbuilt feature of the T cell compartment. However, little is known about the flexibility of T cell recognition in the context of genetically variable pathogens such as HIV-1. In this study, we used a combinatorial library containing 24 billion octamer peptides to char...

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Detalhes bibliográficos
Main Authors: Motozono, Chihiro, Miles, John J., Hasan, Zafrul, Gatanaga, Hiroyuki, Meribe, Stanley C., Price, David A., Oka, Shinichi, Sewell, Andrew K., Ueno, Takamasa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684606/
https://ncbi.nlm.nih.gov/pubmed/23799076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066152
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