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T cell exhaustion due to persistent antigen: Quantity not quality?

T cell exhaustion is characterized by failure to respond to a persistent antigen and is a hallmark of chronic infections and cancer. In this issue, Ritcher et al. examine the importance of the amount of persistent antigen versus the cell type presenting it to induce CD8 T cell exhaustion and the con...

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Detalhes bibliográficos
Main Authors: Zuniga, Elina I., Harker, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684559/
https://ncbi.nlm.nih.gov/pubmed/22949327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242852
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