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Cell-intrinsic interleukin-27 and gp130 cytokine receptor signaling regulates virus specific CD4(+) T cell responses and viral control during chronic infection
The outcome of chronic viral infections, which affect millions of people worldwide, are greatly dependent on CD4(+) T cells. Here we showed that T cell specific ablation of the common interleukin-6 (IL-6) family receptor, gp130, profoundly compromised virus-specific CD4(+) T cell survival, T follicu...
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| Publicat a: | Immunity |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701058/ https://ncbi.nlm.nih.gov/pubmed/23993651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.010 |
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