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Cell-intrinsic interleukin-27 and gp130 cytokine receptor signaling regulates virus specific CD4(+) T cell responses and viral control during chronic infection
The outcome of chronic viral infections, which affect millions of people worldwide, are greatly dependent on CD4(+) T cells. Here we showed that T cell specific ablation of the common interleukin-6 (IL-6) family receptor, gp130, profoundly compromised virus-specific CD4(+) T cell survival, T follicu...
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| 發表在: | Immunity |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701058/ https://ncbi.nlm.nih.gov/pubmed/23993651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.010 |
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