Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

Platelets play a key role in atherogenesis and its complications. Both hypercholesterolemia and increased platelet production promote athero-thrombosis; however, a potential link between altered cholesterol homeostasis and platelet production has not been explored. Transplantation of bone marrow (BM...

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Main Authors: Murphy, Andrew J., Bijl, Nora, Yvan-Charvet, Laurent, Welch, Carrie B., Bhagwat, Neha, Reheman, Adili, Wang, Yiming, Shaw, James A., Levine, Ross L., Ni, Heyu, Tall, Alan R., Wang, Nan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683965/
https://ncbi.nlm.nih.gov/pubmed/23584088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3150
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