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Limited Proteolysis Via Millisecond Digestions in Protease-Modified Membranes

Sequential adsorption of poly(styrene sulfonate) (PSS) and proteases in porous nylon yields enzymatic membrane reactors for limited protein digestion. Although a high local enzyme density (~30 mg/cm(3)) and small pore diameters in the membrane lead to digestion in < 1 s, the low membrane thicknes...

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Detalhes bibliográficos
Main Authors: Tan, Yu-Jing, Wang, Wei-Han, Zheng, Yi, Dong, Jinlan, Stefano, Giovanni, Brandizzi, Federica, Garavito, R. Michael, Reid, Gavin E., Bruening, Merlin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683959/
https://ncbi.nlm.nih.gov/pubmed/22950601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3019153
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