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Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis

Monoclonal antibodies (mAbs) are the fastest growing class of therapeutic drugs, because of their high specificities to target cells. Facile analysis of therapeutic mAbs and their post-translational modifications (PTMs) is essential for quality control, and mass spectrometry (MS) is the most powerfu...

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書目詳細資料
發表在:Anal Chem
Main Authors: Pang, Yongle, Wang, Wei-Han, Reid, Gavin E., Hunt, Donald F., Bruening, Merlin L.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016144/
https://ncbi.nlm.nih.gov/pubmed/26455365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b02739
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