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Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome

Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions thereby maintaining genomic integrity. Dr. Qingyi Wei’s group demonstrated over the last decade that NER fidelity and single nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In...

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Detalles Bibliográficos
Main Authors: Emmert, Steffen, Kraemer, Kenneth H.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683875/
https://ncbi.nlm.nih.gov/pubmed/23760049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.72
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