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Similar nucleotide excision repair capacity in melanocytes and melanoma cells

Sunlight UV exposure produces DNA photoproducts in skin that are repaired solely by nucleotide excision repair in humans. A significant fraction of melanomas are thought to result from UV-induced DNA damage that escapes repair, however, little evidence is available regarding the functional capacity...

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Detalhes bibliográficos
Main Authors: Gaddameedhi, Shobhan, Kemp, Michael G., Reardon, Joyce T., Shields, Janiel M., Smith-Roe, Stephanie L., Kaufmann, William K., Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891231/
https://ncbi.nlm.nih.gov/pubmed/20501836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0095
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