Nucleotide Excision Repair Proteins Rapidly Accumulate but Fail to Persist in Human XP-E (DDB2 Mutant) Cells

The XP-E DNA damage binding protein (DDB2) is involved in early recognition of global genome DNA damage during DNA nucleotide excision repair (NER). We found that skin fibroblasts from 4 newly reported XP-E patients with numerous skin cancers and DDB2 mutations had slow repair of 6-4 photoproducts (...

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Hlavní autoři: Oh, Kyu-Seon, Imoto, Kyoko, Emmert, Steffen, Tamura, Deborah, DiGiovanna, John J., Kraemer, Kenneth. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082610/
https://ncbi.nlm.nih.gov/pubmed/21388382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2011.00909.x
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