Sertraline Slows Disease Progression and Increases Neurogenesis in N171-82Q mouse model of Huntington’s Disease

Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder resulting from CAG repeat expansion in the gene that encodes for the protein huntingtin. To identify neuroprotective compound (s) that can slow down disease progression and can be administered long term with few side ef...

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Main Authors: Duan, Wenzhen, Peng, Qi, Masuda, Naoki, Ford, Eric, Tryggestad, Erik, Ladenheim, Bruce, Zhao, Ming, Cadet, Jean Lud, Wong, John, Ross, Christopher A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683653/
https://ncbi.nlm.nih.gov/pubmed/18403212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.01.015
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