Загрузка...

KAP1 regulates gene networks controlling mouse B lymphoid cell differentiation and function

Chromatin remodeling is fundamental for B cell differentiation. Here, we explored the role in this process of KAP1, the cofactor of KRAB-ZFP transcriptional repressors. B lymphoid-specific Kap1 knockout mice displayed reduced numbers of mature B cells, lower steady-state levels of antibodies and acc...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: de Sio, Francesca R. Santoni, Massacand, Joanna, Barde, Isabelle, Offner, Sandra, Corsinotti, Andrea, Kapopoulou, Adamandia, Bojkowska, Karolina, Dagklis, Antonis, Fernandez, Marylise, Ghia, Paolo, Thomas, James H., Pinschewer, Daniel, Harris, Nicola, Trono, Didier
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683646/
https://ncbi.nlm.nih.gov/pubmed/22452978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-401117
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!