KAP1 Regulates Gene Networks Controlling T cell Development and Responsiveness

The modulation of chromatin status at specific genomic loci controls lymphoid differentiation. Here, we investigated the role played in this process by KAP1, the universal cofactor of KRAB-containing zinc finger proteins (KRAB-ZFP), a tetrapod-restricted family of transcriptional repressors. T lymph...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Santoni de Sio, F.R., Barde, I., Offner, S., Kapopoulou, A., Genolet, R., Corsinotti, A., Bojkowska, K., Thomas, J.H., Luescher, I., Pinschewer, D., Harris, N., Trono, D.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894473/
https://ncbi.nlm.nih.gov/pubmed/22872677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-206177
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