KAP1 regulates gene networks controlling mouse B lymphoid cell differentiation and function

Chromatin remodeling is fundamental for B cell differentiation. Here, we explored the role in this process of KAP1, the cofactor of KRAB-ZFP transcriptional repressors. B lymphoid-specific Kap1 knockout mice displayed reduced numbers of mature B cells, lower steady-state levels of antibodies and acc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: de Sio, Francesca R. Santoni, Massacand, Joanna, Barde, Isabelle, Offner, Sandra, Corsinotti, Andrea, Kapopoulou, Adamandia, Bojkowska, Karolina, Dagklis, Antonis, Fernandez, Marylise, Ghia, Paolo, Thomas, James H., Pinschewer, Daniel, Harris, Nicola, Trono, Didier
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683646/
https://ncbi.nlm.nih.gov/pubmed/22452978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-401117
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