KAP1 regulates gene networks controlling mouse B lymphoid cell differentiation and function

Chromatin remodeling is fundamental for B cell differentiation. Here, we explored the role in this process of KAP1, the cofactor of KRAB-ZFP transcriptional repressors. B lymphoid-specific Kap1 knockout mice displayed reduced numbers of mature B cells, lower steady-state levels of antibodies and acc...

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Hlavní autoři: de Sio, Francesca R. Santoni, Massacand, Joanna, Barde, Isabelle, Offner, Sandra, Corsinotti, Andrea, Kapopoulou, Adamandia, Bojkowska, Karolina, Dagklis, Antonis, Fernandez, Marylise, Ghia, Paolo, Thomas, James H., Pinschewer, Daniel, Harris, Nicola, Trono, Didier
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683646/
https://ncbi.nlm.nih.gov/pubmed/22452978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-401117
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