Alteration of 11β-Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptor by Ethanol in Rat Liver and Mouse Hepatoma Cells

Alcohol is a potential risk factor of type 2 diabetes, but its underlying mechanism is unclear. To explore this issue, Wistar rats and mouse hepatoma cells (Hepa 1–6) were exposed to ethanol, 8 g·kg(−1) ·d(−1) for 3 months and 100 mM for 48 h, respectively. Glucose and insulin tolerance tests in viv...

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Detalhes bibliográficos
Main Authors: Meng, Zhaojie, Bao, Xueying, Zhang, Ming, Wei, Shengnan, Chang, Wenguang, Li, Jing, Chen, Li, Nyomba, B. L. Grégoire
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683472/
https://ncbi.nlm.nih.gov/pubmed/23819126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/218102
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