Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase

Fatty acid amide hydrolase (FAAH), the enzyme responsible for terminating signaling by the endocannabinoid anandamide, plays an important role in the endocannabinoid system, and FAAH inhibitors are attractive drugs for pain, addiction, and neurological disorders. The synthesis, radiosynthesis, and e...

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Autors principals: Sadovski, Oleg, Hicks, Justin W., Parkes, Jun, Raymond, Roger, Nobrega, José, Houle, Sylvain, Cipriano, Mariateresa, Fowler, Christopher J., Vasdev, Neil, Wilson, Alan A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683374/
https://ncbi.nlm.nih.gov/pubmed/23712084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.077
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