Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase

Fatty acid amide hydrolase (FAAH), the enzyme responsible for terminating signaling by the endocannabinoid anandamide, plays an important role in the endocannabinoid system, and FAAH inhibitors are attractive drugs for pain, addiction, and neurological disorders. The synthesis, radiosynthesis, and e...

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Main Authors: Sadovski, Oleg, Hicks, Justin W., Parkes, Jun, Raymond, Roger, Nobrega, José, Houle, Sylvain, Cipriano, Mariateresa, Fowler, Christopher J., Vasdev, Neil, Wilson, Alan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683374/
https://ncbi.nlm.nih.gov/pubmed/23712084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.077
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