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PARP-mediated Repair, Homologous Recombination, and Back-up Non-Homologous End Joining-Like Repair of Single-Strand Nicks
Double-strand breaks (DSBs) in chromosomal DNA can induce both homologous recombination (HR) and non-homologous recombination (NHEJ). Recently we showed that single-strand nicks induce HR with a significant reduction in toxicity and mutagenic effects associated with NHEJ. To further investigate the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683368/ https://ncbi.nlm.nih.gov/pubmed/23684799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.004 |
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