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Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA
The bacterial decoding region of 16S ribosomal RNA has multiple modified nucleotides. In order to study the role of N(4),2′-O-dimethylcytidine (m(4)Cm), the corresponding phosphoramidite was synthesized utilizing 5′-silyl-2′-ACE chemistry. Using solid-phase synthesis, m(4)Cm, 5-methylcytidine (m(5)C...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683315/ https://ncbi.nlm.nih.gov/pubmed/23566761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.010 |
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