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Absolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila
How morphogen gradients are shaped is a major question in developmental biology, but remains poorly understood. Hedgehog (Hh) is a locally secreted ligand that reaches cells at a distance and acts as a morphogen to pattern the Drosophila wing and the vertebrate neural tube. The proper patterning of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683162/ https://ncbi.nlm.nih.gov/pubmed/23789110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134952 |
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