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Absolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila

How morphogen gradients are shaped is a major question in developmental biology, but remains poorly understood. Hedgehog (Hh) is a locally secreted ligand that reaches cells at a distance and acts as a morphogen to pattern the Drosophila wing and the vertebrate neural tube. The proper patterning of...

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Detaylı Bibliyografya
Asıl Yazarlar: Ducuing, Antoine, Mollereau, Bertrand, Axelrod, Jeffrey D., Vincent, Stephane
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683162/
https://ncbi.nlm.nih.gov/pubmed/23789110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134952
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