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Determining the calibration of confidence estimation procedures for unique peptides in shotgun proteomics

The analysis of a shotgun proteomics experiment results in a list of peptide-spectrum matches (PSMs) in which each fragmentation spectrum has been matched to a peptide in a database. Subsequently, most protein inference algorithms rank peptides according to the best-scoring PSM for each peptide. How...

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Detalhes bibliográficos
Main Authors: Granholm, Viktor, Navarro, José C.F., Noble, William Stafford, Käll, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683086/
https://ncbi.nlm.nih.gov/pubmed/23268117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.12.007
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