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Improvements to the Percolator algorithm for peptide identification from shotgun proteomics data sets

Shotgun proteomics coupled with database search software allows the identification of a large number of peptides in a single experiment. However, some existing search algorithms, such as SEQUEST, use score functions that are designed primarily to identify the best peptide for a given spectrum. Conse...

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Detalhes bibliográficos
Main Authors: Spivak, Marina, Weston, Jason, Bottou, Léon, Käll, Lukas, Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710313/
https://ncbi.nlm.nih.gov/pubmed/19385687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr801109k
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