Interferon Regulatory Factor 1 Polymorphisms Previously Associated with Reduced HIV Susceptibility Have No Effect on HIV Disease Progression

INTRODUCTION: Interferon regulatory factor 1 (IRF1) is induced by HIV early in the infection process and serves two functions: transactivation of the HIV-1 genome and thus replication, and eliciting antiviral innate immune responses. We previously described three IRF1 polymorphisms that correlate wi...

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Detalhes bibliográficos
Main Authors: Sivro, Aida, McKinnon, Lyle R., Ji, Hezhao, Kimani, Joshua, Jaoko, Walter, Plummer, Francis A., Su, Ruey-Chyi, Ball, T. Blake
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683001/
https://ncbi.nlm.nih.gov/pubmed/23799084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066253
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