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Epitope Mapping of HIV-Specific CD8(+) T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function

The limited success of HIV vaccine candidates to date highlights our need to better characterize protective cell-mediated immunity (CMI). While HIV-specific CD8(+) T cell responses have been defined largely by measuring gamma interferon (IFN-γ), these responses are not always protective, and it is u...

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Detalhes bibliográficos
Main Authors: Richmond, Meika, McKinnon, Lyle R., Kiazyk, Sandra A. Koesters, Wachihi, Charles, Kimani, Makobu, Kimani, Joshua, Plummer, Francis A., Ball, T. Blake
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020503/
https://ncbi.nlm.nih.gov/pubmed/21084478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01707-10
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