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Expression of ST3GAL4 Leads to SLe(x) Expression and Induces c-Met Activation and an Invasive Phenotype in Gastric Carcinoma Cells

Sialyl-Lewis X (SLe(x)) is a sialylated glycan antigen expressed on the cell surface during malignant cell transformation and is associated with cancer progression and poor prognosis. The increased expression of sialylated glycans is associated with alterations in the expression of sialyltransferase...

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Detalhes bibliográficos
Main Authors: Gomes, Catarina, Osório, Hugo, Pinto, Marta Teixeira, Campos, Diana, Oliveira, Maria José, Reis, Celso A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682978/
https://ncbi.nlm.nih.gov/pubmed/23799130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066737
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